Contraindicated (one)pentobarbital will lessen the extent or outcome of fostemsavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the extent or result of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will lower the level or result of cyclosporine by impact